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Percutaneous nephrolithotomy in children: early and late anatomical and functional results
Mohamed S Dawaba1, Ahmed A Shokeir, Ashraf T Hafez
1Urology & Nephrology Center, Mansoura University, Mansoura, Egypt.
Insights
Percutaneous nephrolithotomy (PCNL) is a safe and effective treatment for pediatric kidney stones. This procedure improves renal function and avoids scarring in children, offering excellent long-term results.
Area of Science:
- Pediatric Urology
- Nephrolithiasis Management
- Minimally Invasive Surgery
Background:
- Renal calculi in children pose a significant health challenge.
- Percutaneous nephrolithotomy (PCNL) is an established treatment for adult kidney stones.
- Evaluating PCNL's efficacy and safety in pediatric populations is crucial.
Purpose of the Study:
- To assess the early and late anatomical outcomes of PCNL in children.
- To evaluate the functional results of PCNL in pediatric patients.
- To determine the safety profile of PCNL in the pediatric population.
Main Methods:
- A cohort of 65 children (72 kidneys) with renal calculi underwent PCNL.
- Patients were followed for 6 to 72 months, with regular check-ups.
- Renal scarring and glomerular filtration rate (GFR) were assessed using specialized scans.
Main Results:
- High stone-free rates were achieved: 86% after single PCNL, 93% at discharge, and 100% at 3 months.
- Early complications were minimal (bleeding, perforation, fever).
- Long-term follow-up showed no renal scarring and a statistically significant improvement in GFR (p <0.01).
Conclusions:
- PCNL is a safe and effective treatment for pediatric renal calculi.
- The procedure leads to improved renal function without causing renal scarring.
- PCNL offers favorable long-term outcomes for children with kidney stones.
Purpose:
We report our experience with percutaneous nephrolithotomy (PCNL) in children, and evaluate its early and late anatomical and functional results.
Materials And Methods:
A total of 65 children with renal calculi were treated with PCNL. Patient age at operation ranged from 9 months to 16 years (mean +/- SD of 5.9 +/- 0.9 years), and 27 (41.5%) were younger than 5 years. Seven patients had bilateral renal stones and, therefore, the number of kidneys treated by PCNL was 72. The patients were followed regularly every 3 months during year 1 and every 6 months thereafter. Renal scans using technetium dimercapto-succinic acid for detection of renal scarring and technetium diethylenetetramine-pentaacetic acid for determination of selective glomerular filtration rate (GFR) were performed in all patients at least once during followup, which ranged from 6 to 72 months (mean +/- SD 40 +/- 10).
Results:
Early complications included significant intraoperative bleeding in 1 case, renal pelvis perforation in 1 and transient fever in 2. Mean hospital stay +/- SD was 3 +/- 1.2 days (range 2 to 21). Of the renal units 62 (86%) were stone-free after a single PCNL, and the remaining 10 with residual stones were treated with a second look PCNL (4) and shock wave lithotripsy (6). Stone-free rates at hospital discharge and at 3 months were 93% and 100%, respectively. During followup 6 patients (9%) had recurrence of small renal stones and were successfully treated with shock wave lithotripsy. None of the kidneys had scarring on dimercapto-succinic acid renal scan. All of the kidneys except 1 showed improvement or stabilization of the corresponding GFR determined by diethylenetetraminepentaacetic acid renal scan. Comparison of the mean preoperative GFR of the corresponding kidney (28.8 +/- 11.2 ml per minute) with mean value at followup (36.1 +/- 9.9) showed an increase of statistical significance (p <0.01).
Conclusions:
PCNL is a safe and effective procedure for the treatment of children with renal calculi. At long-term followup the procedure improves renal function without renal scarring.
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