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[Single-lung transplantation and contralateral lung volume reduction for emphysema]
Jing-yu Chen1, Ming-feng Zheng, Yi-jun He
1Department of Thoracic Surgery, Fifth People's Hospital of Wuxi, Affiliated Hospital of Jiangnan University, Wuxi 214073, China.
Summary
Single-lung transplantation with contralateral lung volume reduction effectively treated end-stage emphysema. This combined approach improved lung function and managed native lung hyperinflation in a ventilated patient.
Area of Science:
- Cardiothoracic Surgery
- Pulmonary Medicine
- Transplantation Immunology
Background:
- End-stage emphysema necessitates advanced treatment options.
- Lung transplantation is a viable option for severe respiratory failure.
- Native lung hyperinflation can complicate post-transplant recovery.
Observation:
- A 47-year-old male with end-stage emphysema underwent left-lung transplantation.
- Contralateral lung volume reduction was performed due to subacute native lung hyperinflation.
- The patient required mechanical ventilation and tracheostomy post-operatively.
Findings:
- Successful left-lung transplantation was performed with a 390-minute cold ischemic time.
- Contralateral lung volume reduction addressed native lung hyperinflation on postoperative day 7.
- The patient was weaned from mechanical ventilation on postoperative day 26.
- Acute rejection episodes on postoperative days 9 and 15 were successfully treated.
Implications:
- Single-lung transplantation combined with contralateral lung volume reduction is effective for end-stage emphysema.
- This strategy can successfully manage subacute native lung hyperinflation.
- Long-term outcomes require further investigation.