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Malignant gastric carcinoids with liver metastasis
Fu-Sheng Wu1, Xiong-Fei Yu, Li-Song Teng
1Department of Surgical Oncology, First Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou 310003, China. qiouhang@mail.hz.zj.cn
Hepatobiliary & Pancreatic Diseases International : HBPD INT
|August 18, 2004
Summary
Malignant gastric carcinoids frequently metastasize to the liver. Surgical treatment combined with other therapies can improve survival rates for patients with these rare tumors.
Area of Science:
- Gastroenterology
- Oncology
- Surgical Pathology
Background:
- Malignant gastric carcinoids are rare neuroendocrine tumors.
- Liver metastasis is a common complication, occurring synchronously or metachronously.
- Resection offers potential cure or palliation due to slow tumor growth.
Purpose of the Study:
- To evaluate clinicopathologic characteristics of malignant gastric carcinoids.
- To analyze diagnostic and management strategies.
- To assess outcomes in patients with liver metastases.
Main Methods:
- Retrospective review of seven patients with malignant gastric carcinoids.
- Data collected between 1990 and 2002.
- Follow-up analysis of patient outcomes.
Main Results:
- All seven patients presented with liver metastases.
- Metastases were synchronous in 3 patients and metachronous in 4.
- Survival varied, with two patients surviving over 3 and 5 years, while others had shorter survival times post-operation.
Conclusions:
- Malignant gastric carcinoids exhibit a high propensity for liver metastasis.
- Combined surgical and therapeutic approaches can significantly extend patient survival.
- Multidisciplinary management is crucial for optimizing outcomes.