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Coagulation parameters as predictors of DIC in patients with intact aortic aneurysm

M M Jeleńska1

  • 1Department of General, Vascular and Transplant Surgery, Medical University of Warsaw, Poland, 1A Banacha Str. 02-097 Warsaw, Poland. mariamagdalenaj@poczta.onet.pl.

Hamostaseologie
|August 18, 2004
PubMed

Insights

Compensated disseminated intravascular coagulation (DIC) is common in patients with abdominal aortic aneurysms (AAA), even without bleeding. Laboratory tests can identify this condition, allowing for preoperative anticoagulation to improve surgical hemostasis.

Area of Science:

  • Vascular Surgery
  • Hematology
  • Coagulation Science

Background:

  • Clinically overt disseminated intravascular coagulation (DIC) is rare before surgery for aortic aneurysms.
  • Large or expanding aortic aneurysms increase the risk of coagulopathy.
  • Compensated DIC in aortic aneurysm patients is likely frequent and underdiagnosed.

Purpose of the Study:

  • To investigate the prevalence of compensated disseminated intravascular coagulation (DIC) in patients with abdominal aortic aneurysms (AAA).
  • To assess the utility of laboratory tests in identifying compensated DIC.
  • To evaluate the potential benefits of preoperative anticoagulation for intraoperative hemostasis.

Main Methods:

  • Analysis of laboratory tests documenting activated coagulation and fibrinolysis in patients with abdominal aortic aneurysms (AAA).
  • Identification of compensated disseminated intravascular coagulation (DIC) in the absence of overt bleeding.
  • Correlation of compensated DIC findings with the need for preoperative anticoagulation.

Main Results:

  • Compensated disseminated intravascular coagulation (DIC) was identified in approximately one-third of patients with abdominal aortic aneurysms (AAA).
  • Laboratory evidence of activated coagulation and fibrinolysis was observed in these patients, despite the absence of clinical bleeding.
  • The identification of compensated DIC facilitated the implementation of preoperative anticoagulation strategies.

Conclusions:

  • Compensated disseminated intravascular coagulation (DIC) is a frequent, yet often underdiagnosed, condition in patients with abdominal aortic aneurysms (AAA).
  • Laboratory diagnostics are crucial for recognizing compensated DIC.
  • Preoperative anticoagulation in identified cases can optimize intraoperative hemostasis and patient outcomes.

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