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Updated: Aug 2, 2026
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An Isolated Working Heart System for Large Animal Models
Published on: June 11, 2014
A new method for exposing the animal's heart with maintenance of natural breathing
Yi Zhang1, Youxiang Pan, Changjin Liu
1Department of Physiology, School of Basic Medical Sciences, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430030, China.
Abstract:
In the experimental study on the electrophysiology and functions of heart in the animal, the thorax should be opened to expose the heart, at the same time natural breathing is maintained instead of artificial breathing. The key procedure of this new method is to avoid injuring the pleural cavity, so pneumothorax can be prevented. By means of this new method some subject studies have been finished.
