Jove
Visualize
Contact Us

Related Experiment Videos

Analytical quality specifications for common reference intervals.

Carmen Ricós1, Maria Vicenta Doménech, Carmen Perich

  • 1Laboratoris Clinics Hospital Universitari Vall d'Hebron, Barcelona, Spain. cricos@hg.vhebron.es

Clinical Chemistry and Laboratory Medicine
|August 26, 2004
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

The neglected issue of pyridoxal- 5' phosphate.

Clinical chemistry and laboratory medicine·2025
Same author

Systematic review and meta-analysis of biological variation data of urine albumin, albumin to creatinine ratio and other markers in urine.

Clinica chimica acta; international journal of clinical chemistry·2024
Same author

Compliance to specifications in an external quality assurance program: did new biological variation estimates of the European Federation of Laboratory Medicine (EFLM) affect the quality of laboratory results?

Advances in laboratory medicine·2023
Same author

Advances in laboratory medicine·2023
Same author

Models to estimate biological variation components and interpretation of serial results: strengths and limitations.

Advances in laboratory medicine·2023
Same author

Critical appraisal and meta-analysis of biological variation studies on glycosylated albumin, glucose and HbA<sub>1c</sub>.

Advances in laboratory medicine·2023
Same journal

Ethical evaluation of reflex and reflective testing in conformity with ISO 15189:2022 at the value-based laboratory medicine era.

Clinical chemistry and laboratory medicine·2026
Same journal

Emerging blood-based diagnostic strategies for tuberculosis.

Clinical chemistry and laboratory medicine·2026
Same journal

Homocitrulline and 3-year mortality in older hospitalised adults: an exploratory study.

Clinical chemistry and laboratory medicine·2026
Same journal

Impact of age partitioning on classification discordance in pediatric ferritin reference intervals.

Clinical chemistry and laboratory medicine·2026
Same journal

National implementation of LOINC: translation methodology and experience from the Polish laboratory terminology standardization project.

Clinical chemistry and laboratory medicine·2026
Same journal

Harmonization of measurement units: mission impossible or ethical imperative?

Clinical chemistry and laboratory medicine·2026
See all related articles
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Establishing quality specifications for laboratory test comparisons, both cross-sectional and longitudinal, is crucial for accurate patient health assessment. Collaborative efforts in analytical quality ensure reliable results across different laboratories.

Area of Science:

  • Clinical Laboratory Science
  • Analytical Chemistry
  • Medical Diagnostics

Background:

  • Laboratory test interpretation relies on comparing results to reference values (cross-sectional or longitudinal).
  • Quality specifications for cross-sectional comparisons are established, but less attention has been given to longitudinal comparisons.
  • Longitudinal comparisons assess true changes in patient health status based on consecutive results.

Purpose of the Study:

  • To discuss clinical and laboratory factors for quality specifications in reference comparisons.
  • To highlight the importance of longitudinal comparison quality specifications.
  • To explore achieving analytical quality and result transferability between laboratories.

Main Methods:

  • Review of quality specifications for cross-sectional comparisons, considering analytical bias and imprecision.

Related Experiment Videos

  • Discussion of criteria for longitudinal comparisons, incorporating biological and analytical variation.
  • Examination of clinical considerations and laboratory-related factors influencing reference comparisons.

    • Main Results:

    • Different analytical methods can yield comparable results when common quality goals are met.
    • Collaborative efforts and established quality specifications facilitate result transferability.
    • Achieving high analytical quality is possible through shared goals and dedication to healthcare quality.

    Conclusions:

    • Quality specifications for both cross-sectional and longitudinal laboratory test comparisons are essential.
    • Standardized quality goals and inter-laboratory collaboration can ensure comparable and transferable results.
    • A commitment to analytical quality is key for reliable patient health status assessment across laboratories.