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Globus pallidus calcification in Down syndrome with progressive neurologic deficits
S Okano1, Y Takeuchi, E Kohmura
1Department of Pediatrics, Kyoto Prefectural University of Medicine, Japan.
Pediatric Neurology
|January 1, 1992
Abstract:
We report a 10-year-old Down syndrome patient who developed dystonia, choreoathetosis, dysarthria, and dysphagia beginning with hemiparesis. Cranial computed tomography disclosed bilateral calcification in the globus pallidus which resembled a sign of premature aging. Conversely, the clinical course and magnetic resonance imaging findings resembled those of Hallervorden-Spatz syndrome.