Recent advances in the treatment of gestational diabetes

Despite four decades of research there is a lack of international consensus on the screening, diagnosis, treatment and follow up of gestational diabetes mellitus (GDM). Currently, GDM is managed by diet modification, exercise and exogenous human insulin. During the last decade, several insulin analogues and oral antihyperglycaemic drugs have revolutionised the management of diabetes mellitus in non-pregnant women. Most of these recent drugs still remain investigational in GDM due to concerns about their safety in pregnancy. This review will focus primarily on the pharmacological treatment of GDM. It will objectively assess the value of these exciting new drugs in pregnancy as they could potentially benefit every woman with GDM.