Related Experiment Video
Updated: Aug 22, 2026

Four-Dimensional CT Analysis Using Sequential 3D-3D Registration
Published on: November 23, 2019
In vivo tibiofemoral contact analysis using 3D MRI-based knee models
Louis E DeFrate1, Hao Sun, Thomas J Gill
1Bioengineering Laboratory, Harvard Medical School, Massachusetts General Hospital, 55 Fruit Street, GRJ 1215, Boston, MA 02114, USA.
Abstract:
This paper quantified the motion of the tibiofemoral contact points during in vivo weight bearing flexion using MRI- based 3D knee models and two orthogonal fluoroscopic images. The contact points on the medial and lateral tibial plateau were calculated by finding the centroid of the intersection of the tibial and femoral cartilage layers and by using the bony geometry alone. Our results indicate that the medial femoral condyle remains in the central portion of the tibial plateau and the lateral condyle translates posteriorly with increasing flexion. Using the bony contact model increased the total translation of the medial and lateral condyles by 250 and 55%, respectively, compared to the cartilage contact model. These results suggest that using the bony geometry alone may not accurately represent the articular surfaces of the knee. Articular cartilage geometry may have to be used to accurately quantify tibiofemoral contact.
