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Updated: Jul 12, 2026

Combining QD-FRET and Microfluidics to Monitor DNA Nanocomplex Self-Assembly in Real-Time
Published on: August 26, 2009
Discrete nanostructures of quantum dots/Au with DNA
Aihua Fu1, Christine M Micheel, Jennifer Cha
1Department of Chemistry, University of California-Berkeley, Lawrence Berkeley National Laboratory, Berkeley, CA 94720, USA.
Abstract:
Nanostructures of colloidal CdSe/ZnS core/shell quantum dots (QDs) surrounded by a discrete number of Au nanoparticles were generated via DNA hybridization and purified by gel electrophoresis. Statistics from TEM analysis showed a high yield of designed structures. The distance between Au particles and QD, the number of Au around the central QD, and the size of Au and QD can be adjusted. Rationally designed structures such as these hold great promise for researching the physical interactions between semiconductor and Au nanoparticles and for developing more efficient nanoprobes.
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