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Antroduodenal motility in neurologically handicapped children with feeding intolerance

Steven L Werlin1

  • 1Department of Pediatrics, Medical College of Wisconsin, Children's Hospital of Wisconsin, Milwaukee, WI United States of America. swerlin@mail.mcw.edu

BMC Gastroenterology
|September 3, 2004
PubMed

Insights

Feeding intolerance in neurologically handicapped children is often linked to foregut dysmotility. This condition, affecting upper gastrointestinal function, may be more prevalent than previously thought.

Area of Science:

  • Pediatric Gastroenterology
  • Neurodevelopmental Disorders

Background:

  • Dysphagia and feeding intolerance are prevalent in children with neurological impairments.
  • Identifying the causes of feeding intolerance is crucial for managing these complex cases.

Purpose of the Study:

  • To investigate the etiologies of feeding intolerance in neurologically handicapped children experiencing difficulties with tube feedings.

Main Methods:

  • Retrospective chart review of 18 neurologically handicapped children with gastrostomy feeding intolerance.
  • Analysis of medical history, diagnoses, fundoplication history, and gastrointestinal function tests (barium radiography, endoscopy, antroduodenal manometry).

Main Results:

  • Abnormal findings were noted in barium upper gastrointestinal series (5/11), liquid phase gastric emptying tests (7/14), and endoscopy (2/16).
  • All 18 children exhibited abnormal antroduodenal motility, indicating widespread foregut dysmotility.

Conclusions:

  • Foregut dysmotility is a significant, potentially underrecognized, cause of feeding intolerance in neurologically handicapped children.
  • Abnormal antroduodenal motility may explain many upper gastrointestinal symptoms in this population.
Abstract

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