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Related Experiment Videos

Delayed interval delivery and infant survival: a population-based study.

Jun Zhang1, Brady Hamilton, Joyce Martin

  • 1Division of Epidemiology, Statistics and Prevention Research, National Institute of Child Health and Human Development, National Institutes of Health/DHHS, Bethesda, MD, USA.

American Journal of Obstetrics and Gynecology
|September 3, 2004
PubMed
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Delaying delivery in multifetal pregnancies significantly improves infant survival rates. This strategy, particularly for twins delivered before 30 weeks, offers a better chance of survival to one year.

Area of Science:

  • Perinatology
  • Maternal-Fetal Medicine
  • Neonatology

Background:

  • Delayed delivery of a second twin in multifetal pregnancies is a complex intervention.
  • The impact of delaying delivery on infant survival outcomes remains incompletely understood.

Purpose of the Study:

  • To evaluate the association between delayed delivery of the second twin and infant survival.
  • To compare perinatal outcomes between delayed and non-delayed twin deliveries.

Main Methods:

  • Analysis of the US 1995-1998 Matched Multiple Birth File.
  • Inclusion of 200 twin pregnancies with delayed delivery (≥2 days) and matched controls.
  • Comparison of infant survival and perinatal outcomes.

Main Results:

Related Experiment Videos

  • Delayed delivery was associated with a 131g average increase in birth weight per week of delay.
  • Survival to one year increased significantly in delayed second twins (56%) compared to non-delayed twins (24%).
  • A small percentage (11%) of second twins in delayed deliveries experienced fetal death before 24 weeks.

Conclusions:

  • Delayed delivery of a second twin before 30 weeks of gestation, for at least two days, is associated with improved infant survival.
  • This strategy offers a potential benefit for improving outcomes in select multifetal pregnancies.