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Updated: Jul 19, 2026
08:40
Methyl-binding DNA capture Sequencing for Patient Tissues
Published on: October 31, 2016
Gene-promoter hypermethylation as a biomarker in lung cancer
1Lung Cancer Program, Lovelace Respiratory Research Institute, Albuquerque, New Mexico 87108, USA. SBelinsk@lrri.org
Nature Reviews. Cancer
|September 3, 2004
Abstract:
Silencing of genes by aberrant promoter hypermethylation is now recognized as a crucial component in cancer initiation and progression. Highly sensitive assays have been developed to assess gene-promoter methylation in biological fluids. The detection of methylated genes in sputum could lead to the development of a screening test to non-invasively identify early cancer in high-risk people.
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