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Microfluidic Chips Controlled with Elastomeric Microvalve Arrays
Published on: October 1, 2007
Elastomer-glass micropump employing active throttles
I D Johnston1, J B Davis, R Richter
1Science and Technology Research Centre, University of Hertfordshire, UK.
The Analyst
|September 3, 2004
Summary
We developed a novel microfluidic pump using glass and PDMS that throttles flow instead of using valves. This design allows for pumping suspensions and offers bidirectional flow control.
Area of Science:
- Microfluidics
- Materials Science
- Biomedical Engineering
Background:
- Microfluidic devices require precise fluid control.
- Traditional microfluidic pumps often use valves that can clog with suspensions.
- Developing pumps with improved tolerance for particulate matter is crucial for many applications.
Purpose of the Study:
- To introduce a new microfluidic pump, the Micro Throttle Pump (MTP).
- To demonstrate a novel fluid control mechanism using flow throttling.
- To assess the MTP's performance and potential for handling suspensions.
Main Methods:
- Constructed the MTP using glass and microstructured poly(dimethylsiloxane) (PDMS).
- Employed piezoelectrically (PZT) actuated deformation of PDMS flow constrictions (throttles).
- Utilized time-sequencing of PZT actuation for bidirectional pumping.
Main Results:
- Achieved a pumping rate of 300 microliters per minute.
- Demonstrated the capability to generate a back-pressure of 5.5 kPa.
- Showcased the MTP's potential for solid-phase suspension tolerance due to throttling mechanism.
Conclusions:
- The Micro Throttle Pump (MTP) offers a promising alternative to conventional microfluidic pumps.
- The use of PDMS and throttling provides advantages in flexibility and suspension handling.
- The MTP design facilitates bidirectional flow and is suitable for various microfluidic applications.
