Related Experiment Video
Updated: Aug 22, 2026

Investigation into Deep Breathing through Measurement of Ventilatory Parameters and Observation of Breathing Patterns
Published on: September 16, 2019
Comparison of computerized methods for detecting the ventilatory thresholds
Edil Luis Santos1, Antonio Giannella-Neto
1Biomedical Engineering Program, Graduate School of Engineering, Federal University of Rio de Janeiro, PO Box 68510, 21945-970 Rio de Janeiro, Brazil.
Abstract:
The aim of this study was to compare computerized automatic methods to detect the ventilatory threshold (VT). Thirty apparently healthy and physically active volunteers [22.5 (6.5) years; 1.72 (0.08) m; 71.9 (8.5) kg] were submitted to a progressive and maximal cycle exercise. The gas exchange was monitored breath-by-breath with a fast gas analyser. The VT and respiratory compensation (RC) were automatically detected based on the respiratory exchange ratio, the ventilatory equivalent for O2 and the ventilatory equivalent for CO2, pulmonary ventilation, end-tidal PO2 and PCO2, and v-slope. In addition, VT and RC were also determined independently by visual inspection by two experienced investigators, and the results were compared with those of the automatic procedures. The automatic VT averaged 77% of the maximal VO2 and the RC 88%. The agreement between the experienced observers was very close [mean difference: 44.4 (16.1) ml, r = 0.94, not significant]. Data were expressed as the mean value together with the standard deviation in each case. The automatic and visual inspection procedures did not present significant differences, resulting in 29.6 (29.6) ml with a reliability of r = 0.86. All methods were significantly correlated for VT and RC (r = 0.93 on average, P < 0.01). ANOVA did not show differences between either the VT methods (P = 0.131) or the RC methods (P = 0.41). In conclusion, the present study has compared several simultaneous breath-by-breath ergospirometric methods that are used to describe the anaerobic threshold, showing high confidence when compared to visual inspection. No statistical differences were found between the VT and RC techniques for physically active subjects indicating that these methods may be equally effectively employed.
Related Concept Videos
Mechanical Ventilation II: Invasive Ventilation
Negative-Pressure Ventilators
Negative-pressure ventilators create a vacuum around the chest or body to draw air into the lungs, simulating breathing. This method does not require an...
Assessment of Ventilation I: Respiratory Rate
A Ventilation assessment is critical for monitoring a patient's health status. Respiration, one of the most accessible vital signs, provides insights into the function of numerous body systems and can indicate serious health issues, such as brainstem injuries from head trauma.
Critical Guidelines for Assessing Ventilation:
Mechanical Ventilation I: Indication and Settings
Mechanical Ventilation III: Noninvasive Ventilation
Noninvasive Positive-Pressure Ventilation (NIPPV)
Ventilatory Modes
There are three ventilatory modes: full support, partial support, and spontaneous. These are described below.
Full Support Modes
Full support modes include controlled mechanical ventilation, continuous mandatory...
Assessment of Diffusion and Perfusion
The Role of Diffusion in Respiration
Diffusion is the process by which molecules move from an area of higher concentration to an area of lower concentration. In the respiratory system, this principle...
