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Pre-surgical treatment of uterine myomas with LH-RH agonists
F D'Addato1, A Repinto, C Andreoli
1University of Turin, Vercelli Midwifery School, Ospedale S. Andrea, Italy.
Clinical and Experimental Obstetrics & Gynecology
|January 1, 1992
Abstract:
Twenty-five non-menopausal women with uterine myomas were treated with LHRH-analogues for 3-6 months. An average reduction of 40% in uterine volume was observed. One patient refused to complete her therapy, three had no more menses after the interruption of treatment, nine underwent myomectomy within four weeks of their final administration, while in 12 cases hysterectomy was performed. In all cases the decrease in uterine volume induced by the analogue allowed a more limited intervention and prevented excessive blood loss.