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Approaches to imprinted stationary phases for affinity capillary electrochromatography
Milena Quaglia1, Börje Sellergren, Ersilia De Lorenzi
1Department of Pharmaceutical Chemistry, Viale Taramelli 12, University of Pavia, 27100 Pavia, Italy.
Journal of Chromatography. A
|September 10, 2004
Summary
This review explores combining molecular imprinting with capillary electrochromatography for advanced affinity separations. The focus is on creating robust, reproducible, and accessible capillary-based separation media.
Area of Science:
- Analytical Chemistry
- Separation Science
Background:
- Molecular imprinting creates specific binding sites in polymers for target molecules.
- Capillary electrochromatography offers high separation efficiency and selectivity.
Purpose of the Study:
- To review the combination of molecular imprinting and capillary electrochromatography.
- To discuss approaches for creating effective capillary-based affinity separation media.
Main Methods:
- Literature review of combined molecular imprinting and capillary electrochromatography techniques.
- Comparison of different strategies for developing affinity separation media.
Main Results:
- Identified various approaches to integrate molecular imprinting into capillary electrochromatography.
- Highlighted the potential for robust and reproducible affinity separations.
Conclusions:
- The synergy between molecular imprinting and capillary electrochromatography offers promising avenues for affinity-based separations.
- Further development aims for easily accessible and high-performance separation media.