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The impact of cardiac complications on outcome in the SAH population
1University of Pittsburgh School of Nursing, Pittsburgh, PA 15261, USA. ecrago@pitt.edu
Insights
Cardiac complications negatively impact outcomes for acute subarachnoid hemorrhage (SAH) patients. These effects on quality of life and daily functioning were observed up to six months post-hemorrhage.
Area of Science:
- Neurology
- Cardiology
- Critical Care Medicine
Background:
- Acute subarachnoid hemorrhage (SAH) is a critical neurological event.
- Cardiac complications (CdCs) are common in SAH patients.
- The impact of CdCs on SAH patient outcomes requires further elucidation.
Purpose of the Study:
- To investigate the association between cardiac complications (CdCs) and patient outcomes following aneurysmal subarachnoid hemorrhage (SAH).
Main Methods:
- Eighty-one adult aneurysmal SAH patients with significant neurological deficits were enrolled.
- Cardiac complications included ECG changes, myocardial necrosis, arrhythmias, and pulmonary edema.
- Patient outcomes were assessed at 3, 6, and 12 months using validated scales (MRS, GOS, Barthel Index, SF-36).
Main Results:
- Cardiac complications occurred in 33% of SAH patients, with arrhythmias and pulmonary edema being most frequent.
- No significant difference in mortality was observed between patients with and without CdCs.
- Significant differences in functional outcomes (Barthel, SF-36) and trends in GOS and MRS were noted at 3 months, with SF-36 differences persisting at 6 months.
Conclusions:
- Cardiac complications may exert a negative influence on the functional outcomes of SAH patients.
- The impact of CdCs on patient recovery and quality of life is evident up to six months post-hemorrhage.
Objectives:
To determine the impact of cardiac complications (CdCs) on outcomes in patients with acute subarachnoid hemorrhage (SAH).
Patients And Methods:
Eighty-one adult aneurysmal SAH patients with a fisher grade >1 and/or a Hunt and Hess grade >2 were recruited for this study. CdCs were defined as electrocardiogram (ECG) changes, myocardial necrosis, arrythmias, or pulmonary edema. Outcomes were assessed at 3, 6 and 12 months by telephone interview using the Modified Rankin Scale (MRS), Glasgow Outcome Scale (GOS), Barthel Index and Medical Outcome study Short Form-36 (SF-36).
Results:
The CdCs occurred in 33% of patients. The most common CdCs were arrythmias and pulmonary edema (30%). There was no significant difference in mortality between the two groups. At 3 months there was a significant difference in the Barthel (P = 0.007) and the SF-36 (P = 0.014) with trends in the GOS (P = 0.049) and the MRS (P = 0.063). At 6 months a significant difference remained in the SF-36 (P = 0.028) and a trend in the Barthel (P = 0.069).
Conclusion:
Results show that CdCs may negatively impact outcomes in SAH patients up to 6 months following hemorrhage.
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