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Fusospirochetosis causing necrotic oral ulcers in patients with HIV infection
Carlos Salama1, Douglas Finch, Edward J Bottone
1Division of Infectious Diseases, Elmhurst Hopsital Center, NY, USA. csalama@yahoo.com
Abstract:
Under certain permissive circumstances, normally occurring fusiform bacteria and Borrelia spirochetes can result in a symbiotic overgrowth that leads to necrotic oral ulcers (stomatitis), gingivitis, and periodontitis. These lesions are collectively known as oral fusospirochetosis and may be under-appreciated in patients with HIV infection and AIDS. Fusospirochetal oral ulcers in patients with HIV are often large, necrotic, and malodorous; they respond completely to penicillin. We report 3 patients with HIV infection and fusospirochetal ulcerative stomatitis and review the clinical presentation, microbiologic diagnosis, potential pathogenesis, and treatment of these lesions.
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