Related Experiment Videos
[Is osteoporosis well treated in elderly people?]
1Clinique Rhumatologique et Thérapeutique, CHU Dupuytren, Limoges, France. philippe.bertin@chu-limoges.fr
Abstract:
Osteoporosis is an increase in bone fragility resulting from a decrease in bone mineral density and abnormalities in the bone micro-architecture. The frequency of osteoporosis is increasing with the aging of patients, and its clinical consequences, vertebral or peripheral fractures, are potentially extremely serious, especially in the very elderly. It is probable that osteoporosis is underdiagnosed--and when it is diagnosed it is often not well treated. It should be realised that a loss in bone mineral density is not the only risk factor for osteoporotic fractures: iatrogenic and environmental factors are also involved, and these are responsive to preventive intervention. Although elderly people usually take multiple drugs, drug treatment, initially calcium and vitamin D, but also bisphosphonates, should also be considered for osteoporosis.
Related Concept Videos
Bone Disorders
Bone deposition is also affected by the levels of sex hormones like estrogen and testosterone that promote osteoblast activity and bone matrix synthesis. When the level of these hormones decreases due to aging, it causes a reduction in bone deposition. As a result, bone resorption by osteoclasts...
Drug Dosing: Geriatric Patients
Pharmacokinetics in Geriatric Patients: Effect of Age on Drug Distribution
Pharmacodynamics in Geriatric Patients: Effects of Age
Bone Remodeling
Pharmacokinetics in Geriatric Patients: Effect of Age on Drug Metabolism