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Updated: Aug 22, 2026
Endoscopy Guided Photoablation of Endometrial Cysts using a 980 nm Laser with a Contact Fiber in Mares
Published on: July 16, 2020
A randomized comparison of endometrial laser intrauterine thermotherapy and hysteroscopic endometrial resection
Antonio Perino1, Antonio Castelli, Gaspare Cucinella
1Department of Obstetrics and Gynecology, Istituto Materno Infantile, University of Palermo, via Libertà 112, 90100 Palermo, Italy. perino@unipa.it
Objective:
To investigate the difference of long-term amenorrhea rate in patients with menorrhagia treated by endometrial laser intrauterine thermal therapy (ELITT), a new nonhysteroscopic endometrial ablation procedure, versus transcervical hysteroscopic endometrial resection (TCRE).
Design:
Randomized clinical study. Healthy volunteers in an academic research environment.
Setting:
Academic teaching hospital.
Patient(S):
Premenopausal women with abnormal uterine bleeding.
Intervention(S):
Fifty-eight patients were treated with the ELITT procedure and 58 patients with TCRE; both groups were treated with GnRH agonists before the procedure.
Main Outcome Measure(S):
Bleeding status and patient satisfaction after treatment were evaluated as well as the intraoperative complication rate.
Result(S):
At 12 months, the amenorrhea rate was 56% in the ELITT group and 23% in the TCRE group. At 36 months, the figures were 61% for ELITT and 24% for TCRE. No significant complications were recorded for either procedure.
Conclusion(S):
Results of this randomized study demonstrate that both procedures are equally effective in the treatment of menorrhagia. However, the ELITT procedure has proven to be superior in inducing amenorrhea.
