Related Experiment Video

Updated: Aug 3, 2026

Myelin Oligodendrocyte Glycoprotein (MOG35-55) Induced Experimental Autoimmune Encephalomyelitis (EAE) in C57BL/6 Mice
08:03

Myelin Oligodendrocyte Glycoprotein (MOG35-55) Induced Experimental Autoimmune Encephalomyelitis (EAE) in C57BL/6 Mice

Published on: April 15, 2014

Full recovered meningoencephalomyelitis caused by mumps virus

L Savaş1, Z Arlier, A Akçali

  • 1Mustafa Kemal University School of Medicine, Antakya, Turkey.

European Journal of Neurology
|September 24, 2004
PubMed

Insights

Mumps virus rarely causes myelitis, but can lead to severe meningoencephalomyelitis in young patients. This case highlights the potential for mumps virus to cause serious central nervous system complications.

Area of Science:

  • Neurology
  • Virology
  • Pediatrics

Background:

  • Mumps virus commonly causes meningitis, a central nervous system complication.
  • Encephalitis, cranial nerve palsies, and poliradiculoneuritis are less frequent complications of mumps virus.
  • Myelitis due to mumps virus infection is exceptionally rare.

Observation:

  • A young male presented with symptoms suggestive of a severe central nervous system (CNS) inflammatory process.
  • Magnetic resonance imaging (MRI) revealed lesions consistent with severe acute transverse myelitis.
  • The patient's clinical presentation and diagnostic findings pointed towards a viral etiology.

Findings:

  • The case involved a young male diagnosed with meningoencephalomyelitis.
  • Mumps virus was identified as the causative agent.
  • This diagnosis was established despite the rarity of myelitis caused by mumps.

Implications:

  • This case underscores the potential for mumps virus to cause severe and rare neurological complications beyond meningitis.
  • It highlights the importance of considering mumps virus in the differential diagnosis of acute myelitis and encephalitis in children and young adults.
  • Further research may be warranted to understand the pathogenesis of severe CNS manifestations of mumps virus.

More Related Videos

A Model for Epilepsy of Infectious Etiology using Theiler's Murine Encephalomyelitis Virus05:33

A Model for Epilepsy of Infectious Etiology using Theiler's Murine Encephalomyelitis Virus

Published on: June 23, 2022

Adjuvant Activity of Mycobacterium paratuberculosis in Enhancing the Immunogenicity of Autoantigens During Experimental Autoimmune Encephalomyelitis06:57

Adjuvant Activity of Mycobacterium paratuberculosis in Enhancing the Immunogenicity of Autoantigens During Experimental Autoimmune Encephalomyelitis

Published on: May 12, 2023

Related Concept Videos

Bacterial Meningitis01:24

Bacterial Meningitis

Bacterial meningitis is a severe infectious disease involving inflammation of the meninges, the protective membranes surrounding the brain and spinal cord. It occurs when pathogenic bacteria cross the blood–brain barrier and enter the cerebrospinal fluid. Common causative organisms include Neisseria meningitidis, Streptococcus pneumoniae, Haemophilus influenzae type b, Listeria monocytogenes, and Escherichia coli K1. The exact route of entry varies by pathogen and host condition.Routes of Entry...
Viral Meningitis01:18

Viral Meningitis

Viral meningitis is the most common form of meningitis and is often referred to as aseptic meningitis to indicate the absence of bacterial involvement. It is generally milder than bacterial meningitis, with symptoms including fever, headache, stiff neck, drowsiness, nausea, photophobia, and vomiting. Rarely, more severe manifestations or death may occur. Common causative agents include enteroviruses, particularly coxsackie A and B viruses and echoviruses, all members of the Enterovirus genus...
Poliomyelitis01:17

Poliomyelitis

Poliomyelitis is caused by poliovirus, a small, non-enveloped, positive-sense RNA virus of the Picornaviridae family and Enterovirus genus. Transmission occurs primarily via the fecal-oral route, often through ingestion of contaminated water or food. The virus initially replicates in the oropharynx and intestinal mucosa, particularly in lymphoid tissues such as the tonsils, Peyer’s patches, and regional lymph nodes. Primary viremia follows, allowing dissemination throughout the body.In most...
Cryptococcal Meningitis01:27

Cryptococcal Meningitis

Cryptococcal meningitis is a life-threatening opportunistic infection predominantly associated with HIV/AIDS, accounting for over 100,000 deaths annually worldwide. However, it also affects individuals with other forms of immunosuppression, including those undergoing immunosuppressive therapy, organ transplant recipients, patients with innate immunodeficiencies, and individuals with hematological disorders. The infection is caused mainly by Cryptococcus neoformans and Cryptococcus gattii,...
Encephalitis l: Introduction01:19

Encephalitis l: Introduction

Encephalitis is inflammation of the brain parenchyma, most often due to infections or autoimmune processes. It presents with neuropsychiatric features such as fever, altered mental status, behavioral changes, cognitive dysfunction, seizures, focal deficits, and sometimes autonomic instability. In some cases, the meninges are also involved, resulting in meningoencephalitis.Infectious CausesInfectious encephalitis is most commonly viral but can also result from bacterial, fungal, or parasitic...
Encephalitis ll: Pathophysiology01:26

Encephalitis ll: Pathophysiology

Encephalitis is inflammation of the brain parenchyma caused by direct viral invasion or immune-mediated mechanisms triggered by infections or tumors. Both processes lead to neuronal injury, disrupted neurotransmission, and diverse neurological symptoms, often with overlapping clinical and pathological features.Autoimmune EncephalitisIn autoimmune encephalitis, antibodies target neuronal antigens on cell surfaces, synapses, or within neurons. A key example is anti-NMDAR encephalitis, which can...