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Oral pemphigus vulgaris: a case report and literature update
N A Robinson1, J F Yeo, Y S Lee
1Department of Oral and Maxillofacial Surgery, Faculty of Dentistry, National University Hospital, Singapore.
Introduction:
Pemphigus vulgaris is a rare cause of oral mucosal ulceration.
Clinical Picture:
A 47-year-old Chinese man presented with a 3-month history of oral ulceration. There were no lesions on the skin or other mucosal sites. Histology and immunostaining were consistent with pemphigus vulgaris.
Treatment:
Systemic and topical corticosteroids were instituted, together with topical antifungals. Conventional periodontal therapy was carried out to improve gingival/oral health.
Outcome:
Control of oral ulceration was achieved with re-establishment of normal oral function. No other sites to date have been involved.
Conclusions:
Chronic oral ulceration can be the sole manifestation of pemphigus vulgaris, at least initially. Early recognition of this lesion may prevent delayed diagnosis and inappropriate treatment of a potentially chronic dermatological condition.
