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Related Experiment Video

Updated: Jul 13, 2026

Functional Human Liver Preservation and Recovery by Means of Subnormothermic Machine Perfusion
08:54

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Published on: April 27, 2015

Waiting for a liver--hidden costs of the organ shortage.

Donald A Brand1, Deborah Viola, Pretam Rampersaud

  • 1Primary Care Research Unit, School of Public Health, New York Medical College, Valhalla, NY 10595, USA. donald_brand@nymc.edu

Liver Transplantation : Official Publication of the American Association for the Study of Liver Diseases and the International Liver Transplantation Society
|September 25, 2004
PubMed
Summary

Increasing organ availability for liver disease patients would not lower overall costs, but would significantly reduce expenses associated with waiting for a transplant.

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Area of Science:

  • Hepatology
  • Transplant Surgery
  • Health Economics

Background:

  • End-stage liver disease (ESLD) management costs are high, with a focus on transplantation expenses.
  • Costs associated with managing complications during the organ transplant waiting period are substantial.
  • Current healthcare spending for ESLD patients is significantly impacted by prolonged waiting times for organs.

Purpose of the Study:

  • To test the hypothesis that increased organ graft availability reduces healthcare costs for liver disease patients.
  • To quantify the economic impact of the organ transplant waiting period on patient management.
  • To evaluate the cost-effectiveness of timely transplantation versus prolonged waiting for ESLD patients.

Main Methods:

  • Retrospective analysis of treatment costs for liver transplant candidates listed between November 1996 and December 1997.
  • Cost estimation included inpatient stays, outpatient visits, and post-transplant medications over 2.5 years.
  • Comparison of actual costs with hypothetical costs assuming immediate transplantation for all candidates.

Main Results:

  • Pre-transplantation costs constituted 41% of the total healthcare expenditure for the cohort.
  • Transplanting all candidates immediately would increase costs by 37% but double the number of transplants.
  • A significant number of patients (19%) died while awaiting an organ, incurring substantial pre-transplant costs.

Conclusions:

  • An adequate supply of donor organs would not decrease overall healthcare spending for ESLD.
  • Savings from eliminating the waiting period would offset a significant portion of the cost of additional transplants.
  • Timely transplantation, enabled by increased organ availability, offers a more cost-effective management strategy for ESLD patients.