Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Carbohydrate supplementation during exercise.

E F Coyle1

  • 1Department of Kinesiology and Health, University of Texas, Austin.

The Journal of Nutrition
|March 1, 1992
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Attenuated relationship between cardiac output and oxygen uptake during high-intensity exercise.

Acta physiologica (Oxford, England)·2011
Same author

The effects of fasting on metabolism and performance.

British journal of sports medicine·2010
Same author

Maximal power and performance during a swim taper.

International journal of sports medicine·2007
Same author

Cardiovascular drift during prolonged exercise: new perspectives.

Exercise and sport sciences reviews·2001
Same author

Effects of beta-adrenergic receptor stimulation and blockade on substrate metabolism during submaximal exercise.

American journal of physiology. Endocrinology and metabolism·2001
Same author

Low-fat diet alters intramuscular substrates and reduces lipolysis and fat oxidation during exercise.

American journal of physiology. Endocrinology and metabolism·2001
Same journal

Considerations for Dietary Supplements After GLP-1RA Treatment: A Narrative Review.

The Journal of nutrition·2026
Same journal

The apple(juice) doesn't fall far from the tree: Children's hydration mirrors their parent's.

The Journal of nutrition·2026
Same journal

Microbial-derived polyphenol metabolites and the gut microbiota: A scoping review of clinical studies.

The Journal of nutrition·2026
Same journal

Hesperidin as an Emerging Nutraceutical in Modern Health and Preventive Medicine: A Narrative Review.

The Journal of nutrition·2026
Same journal

Short-Chain Fatty Acids in Livestock and Aquatic Animals: Metabolic Divergence, Physiological Functions, and Product Development.

The Journal of nutrition·2026
Same journal

Immunomodulatory properties of choline and its dietary forms throughout the lifespan.

The Journal of nutrition·2026
See all related articles

During prolonged strenuous exercise, fatigue is often caused by inadequate carbohydrate oxidation, partly due to hypoglycemia. Carbohydrate feeding delays fatigue by maintaining blood glucose levels and oxidation rates.

Area of Science:

  • Exercise Physiology
  • Sports Nutrition
  • Metabolic Research

Background:

  • Skeletal muscle uses muscle glycogen and plasma glucose for energy during strenuous exercise.
  • With prolonged exercise, there's a shift from muscle glycogen to blood glucose utilization.
  • Hypoglycemia can occur during prolonged exercise, leading to muscle fatigue.

Purpose of the Study:

  • To investigate the role of carbohydrate oxidation in exercise fatigue.
  • To determine the effects of carbohydrate feeding on fuel utilization and fatigue during prolonged exercise.
  • To understand the relationship between blood glucose levels and exercise performance.

Main Methods:

  • Monitoring substrate utilization (muscle glycogen, plasma glucose) during prolonged exercise.

Related Experiment Videos

  • Assessing the impact of carbohydrate feeding on blood glucose concentration and exercise capacity.
  • Measuring maximal oxygen consumption and fatigue onset during exercise protocols.
  • Main Results:

    • Blood glucose levels decline to hypoglycemic levels during prolonged exercise, contributing to fatigue.
    • Carbohydrate feeding delays fatigue by 30-60 minutes by maintaining blood glucose and oxidation rates.
    • Muscle glycogen utilization is minimal when carbohydrate is consumed during exercise, indicating blood glucose as the primary source.

    Conclusions:

    • Inadequate carbohydrate oxidation, often due to hypoglycemia, is a primary cause of fatigue during prolonged strenuous exercise.
    • Carbohydrate supplementation during exercise helps delay fatigue but does not prevent it.
    • There is a limit to the rate at which blood glucose can be utilized for energy, even with supplementation.