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Strychnine poisoning in an adolescent
W Yamarick1, P Walson, J DiTraglia
1Riverside Methodist Hospital, Toledo, Ohio.
Journal of Toxicology. Clinical Toxicology
|January 1, 1992
Summary
A teen survived strychnine poisoning after ingesting a tainted antibiotic capsule. The case highlights severe symptoms like lactic acidosis and rhabdomyolysis, emphasizing the need for prompt diagnosis and treatment of this poisoning.
Area of Science:
- Toxicology
- Pharmacology
- Emergency Medicine
Background:
- Strychnine poisoning is a rare but potentially fatal condition.
- Accidental or intentional ingestion can lead to severe neurological and metabolic disturbances.
Observation:
- A 14-year-old female presented with acute lower extremity stiffness and weakness hours after antibiotic capsule ingestion.
- She developed seizures, severe lactic acidosis (pH 6.86), hyperthermia (40.5°C), and rhabdomyolysis.
Findings:
- Toxicology confirmed strychnine in blood, gastric aspirate, and urine.
- The patient survived despite the critical presentation.
Implications:
- This case underscores the importance of considering environmental toxins in acute neurological presentations.
- Understanding strychnine pharmacokinetics and clinical manifestations is crucial for effective management and improved patient outcomes.