Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Search research articles

Related Experiment Videos

[Assistance in human oocyte fertilization using micromanipulation].

P Barlow¹, P Van der Zwalmen, A Delvigne

¹Unité de Recherche en Reproduction humaine, Hôpital St-Pierre, U.L.B., Bruxelles.

Revue Medicale De Bruxelles

|January 1, 1992

Summary

Subzonal sperm injection (SUZI) and partial zona dissection (PZD) enhance human fertilization rates in cases of severe sperm defects. These micromanipulation techniques offer improved outcomes for in vitro fertilization (IVF) patients.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

Determination of the Thermomigration Force on Adatoms.

Physical review letters·2023

Same author

Protein quality as a complementary functional unit in life cycle assessment (LCA).

The international journal of life cycle assessment·2023

Same author

To culture or not to culture: careful assessment of metabarcoding data is necessary when evaluating the microbiota of a modified-atmosphere-packaged vegetarian meat alternative throughout its shelf-life period.

BMC microbiology·2022

Same author

Editorial: Quality of animal-source foods related to their production and processing conditions.

Animal : an international journal of animal bioscience·2022

Same author

Does the freeze-all strategy improve the cumulative live birth rate and the time to become pregnant in IVF cycles?

Archives of gynecology and obstetrics·2021

Same author

Globalization and health policy space: Introducing the WTOhealth dataset of trade challenges to national health regulations at World Trade Organization, 1995-2016.

Social science & medicine (1982)·2021

Area of Science:

Reproductive biology
Assisted reproductive technology (ART)

Background:

Severe sperm defects pose challenges to natural human fertilization.
Micromanipulation techniques aim to improve gamete interaction and fertilization success.

Observation:

Direct intracytoplasmic sperm injection (ICSI) has theoretical risks and technical difficulties in humans.
Subzonal sperm injection (SUZI) and partial zona dissection (PZD) are established ART methods.

Findings:

Partial zona dissection (PZD) significantly increased fertilization rates from 2.9% to 21.6% in intact oocytes.
PZD resulted in 3 pregnancies (2 ongoing) from 28 attempts in this study.

Implications:

PZD offers a viable option for improving IVF success in cases of male infertility.

Related Experiment Videos

Further evaluation of risks and benefits of PZD and SUZI is warranted.