Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Iron overload and hematologic malignancies.

Massimo Franchini1, Dino Veneri

  • 1Servizio di Immunoematologia e Trasfusione, Centro Emofilia, Azienda Ospedaliera di Verona, 37134 Verona, Italy. massimo.franchini@mail.azosp.vr.it

The Hematology Journal : the Official Journal of the European Haematology Association
|September 28, 2004
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

An unusual case of sodium citrate-dependent artifactual platelet count.

Interventional medicine & applied science·2022
Same author

Pathogenesis of immune thrombocytopenia in common variable immunodeficiency.

Autoimmunity reviews·2020
Same author

Is triple-positive serology for Epstein-Barr virus (VCA-IgG, VCA-IgM, EBNA-IgG) a specific feature of angioimmunoblastic T-cell lymphoma?

Tumori·2019
Same author

Eltrombopag for the treatment of inherited thrombocytopenias: a phase II clinical trial.

Haematologica·2019
Same author

Calcium-Dependent Src Phosphorylation and Reactive Oxygen Species Generation Are Implicated in the Activation of Human Platelet Induced by Thromboxane A2 Analogs.

Frontiers in pharmacology·2018
Same author

Primary sphenoid lymphoma: Focus on imaging.

Tumori·2018
Same journal

Acute myocardial infarction in sickle cell disease: a possible complication of hydroxyurea treatment.

The hematology journal : the official journal of the European Haematology Association·2005
Same journal

Plasma nitric oxide levels used as an indicator of doxorubicin-induced cardiotoxicity in rats.

The hematology journal : the official journal of the European Haematology Association·2005
Same journal

The effect of iron deficiency anemia on the function of the immune system.

The hematology journal : the official journal of the European Haematology Association·2005
Same journal

Liver iron concentration and fibrosis in a cohort of transfusion-dependent patients on long-term desferrioxamine therapy.

The hematology journal : the official journal of the European Haematology Association·2005
Same journal

Malignant diseases of hematopoietic and lymphoid tissues in Chernobyl clean-up workers.

The hematology journal : the official journal of the European Haematology Association·2005
Same journal

Outcome of patients with multiple myeloma and hypertension treated with angiotensin-I-converting enzyme inhibitors during high-dose chemotherapy.

The hematology journal : the official journal of the European Haematology Association·2005
See all related articles

Iron overload is linked to cancer development. This review focuses on the connection between excess iron stores and hematologic malignancies, clarifying this association.

Area of Science:

  • Hematology
  • Oncology
  • Biochemistry

Background:

  • Iron is vital for cell replication and survival.
  • Increased body iron stores are associated with cancer development.
  • The link between iron overload and hepatocellular carcinoma is established, but its role in other cancers is less clear.

Purpose of the Study:

  • To review current knowledge on the association between iron overload and hematologic malignancies.
  • To elucidate the relationship between excess iron and blood cancers.

Main Methods:

  • Literature review of existing studies.
  • Synthesis of current research findings.

Main Results:

  • The association between iron overload and hepatocellular carcinoma is well-documented.

Related Experiment Videos

  • The relationship between iron overload and non-hepatocellular malignancies is not well-defined.
  • This review summarizes the current understanding of iron overload in hematologic malignancies.

    • Conclusions:

    • Excess iron stores may play a role in the development of hematologic malignancies.
    • Further research is needed to fully understand the impact of iron overload on various cancers.
    • Clarifying the iron-cancer link is crucial for potential therapeutic strategies.