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Primary sphenoid lymphoma: Focus on imaging.

Davide Facchinelli1, Enrico Boninsegna2, Marco Barillari2

  • 11 Department of Medicine, Section of Hematology, University of Verona, Verona, Italy.

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|October 2, 2018
PubMed
Summary

Primary sphenoid sinus lymphoma is rare, presenting diagnostic challenges. This case highlights imaging findings in computed tomography, magnetic resonance imaging, and positron emission tomography scans for this unusual lymphoma.

Keywords:
Lymphomadifferential diagnosisimagingotorhinolaryngologysphenoid

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Area of Science:

  • Oncology
  • Radiology
  • Pathology

Background:

  • Primary lymphoma of the sphenoid sinus is an exceptionally rare condition.
  • Diagnostic challenges arise due to its rarity and poorly understood imaging characteristics.

Observation:

  • A 44-year-old patient presented with severe headache, prompting investigation.
  • Initial computed tomography (CT) and magnetic resonance imaging (MRI) revealed a sphenoid sinus mass.

Findings:

  • Imaging suggested a rhinopharyngeal lesion or chordoma, necessitating further evaluation.
  • Histopathological analysis confirmed Diffuse large B-cell lymphoma.
  • Positron emission tomography (PET) scans demonstrated increased fluorodeoxyglucose uptake around the sphenoid bone and multiple spinal lesions.

Implications:

  • This case underscores the importance of considering lymphoma in the differential diagnosis of sphenoid sinus masses.
  • Accurate imaging interpretation and biopsy are crucial for diagnosing rare pathologies like primary sphenoid lymphoma.
  • Understanding the imaging features of this rare lymphoma can aid in earlier detection and management.