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Published on: February 26, 2013
Long-term management of chronic DIC associated with inoperable aortic aneurysm with low molecular weight heparin
1Haematology Department, Doncaster Royal Infirmary, Thorne Road, Doncaster, DN2 5LT, UK. gautam.majumdar@dbh.nhs.uk
Insights
Chronic disseminated intravascular coagulation (DIC), a rare aortic aneurysm complication, can be managed with heparin for inoperable cases. This report details successful long-term dalteparin management for a patient with inoperable aortic aneurysm and chronic DIC.
Area of Science:
- Cardiology
- Hematology
- Vascular Surgery
Background:
- Chronic disseminated intravascular coagulation (DIC) is a rare complication associated with aortic aneurysms.
- Surgical correction is the primary treatment for aortic aneurysms.
- Heparin therapy is an alternative for patients with inoperable aneurysms or persistent DIC post-surgery.
Observation:
- A patient presented with multiple, inoperable aortic aneurysms.
- The patient also had chronic disseminated intravascular coagulation (DIC).
Findings:
- The patient was successfully managed with dalteparin, a low-molecular-weight heparin, over an extended period.
- This case highlights the efficacy of long-term anticoagulation in managing chronic DIC secondary to aortic aneurysms in challenging clinical scenarios.
Implications:
- Long-term anticoagulation with agents like dalteparin can be a viable therapeutic option for chronic DIC in patients with inoperable aortic aneurysms.
- This approach may help control coagulopathy and improve outcomes in select patient populations.
- Further research into anticoagulation strategies for chronic DIC in vascular disease is warranted.
Abstract:
Chronic DIC is a rare complication of aortic aneurysm. Surgical correction is the treatment of choice but for inoperable patients or those with continued DIC after surgery heparin can be used to control the coagulopathy. A case with inoperable multiple aortic aneurysm and chronic DIC managed successfully with dalteparin over a long period is discussed in this report.
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