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Correlates of adherence with transdermal nicotine
Theodore V Cooper1, Margaret W DeBon, Michelle Stockton
1Department of Psychiatry and Human Behavior, The University of Mississippi Medical Center, GV Sonny Montgomery Veteran's Affairs Medical Center, 2500 North State Street, Jackson 39216, USA. tvcooper@psychiatry.umsmed.edu
Addictive Behaviors
|September 29, 2004
Summary
Male gender, intensive treatment, and study completion are linked to higher transdermal nicotine patch adherence. Adherence also predicts smoking cessation success at 6 and 12 months.
Area of Science:
- Behavioral Science
- Addiction Medicine
- Public Health
Background:
- Transdermal nicotine (TN) is a common smoking cessation aid.
- Understanding factors influencing adherence to TN therapy is crucial for treatment efficacy.
- Previous research has explored various predictors of adherence with mixed results.
Purpose of the Study:
- To examine adherence rates to transdermal nicotine (TN) in adults.
- To identify demographic, smoking-related, and treatment-related variables associated with TN adherence.
- To determine the relationship between TN adherence and smoking cessation outcomes.
Main Methods:
- A correlational study involving 619 males and females aged 18+ receiving behavioral interventions.
- Adherence rates were assessed using loglinear and logistic regression analyses.
- Variables included gender, income, age, baseline carbon monoxide, nicotine dependence, quit status, treatment condition, and drop status.
Main Results:
- Male gender, not dropping out, and intensive treatment were associated with greater TN adherence.
- Patch adherence positively correlated with smoking cessation at 6 and 12 months (OR=2.47 and 2.12, respectively).
- Higher adherence was linked to more completed telephone intervention contacts (OR=2.621). Income level showed no association with adherence.
Conclusions:
- Specific characteristics, including male gender and engagement in intensive treatment, predict better adherence to transdermal nicotine therapy.
- Adherence to transdermal nicotine patches is a significant predictor of successful long-term smoking cessation.
- Findings offer insights for optimizing TN therapy in research and clinical practice to improve quit rates.