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From genomics to post-genomics in Aspergillus.

David B Archer1, Paul S Dyer

  • 1School of Biology, University Park, University of Nottingham, Nottingham, NG7 2RD, UK. david.archer@nottingham.ac.uk

Current Opinion in Microbiology
|September 29, 2004
PubMed
Summary

Genome sequencing for Aspergillus species is now available, marking a shift to a post-genomic era. This transition offers new resources and methods to advance research in Aspergillus biology, biotechnology, and medicine.

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Area of Science:

  • Microbiology
  • Genomics
  • Biotechnology

Background:

  • Recent availability of genome sequence data for select Aspergillus species.
  • The field is transitioning from a genomics focus to a post-genomic era for these fungi.

Purpose of the Study:

  • To describe the resources and methodologies supporting Aspergillus research in the post-genomic era.
  • To anticipate advances in fundamental Aspergillus biology and its applications.

Main Methods:

  • Review of available genomic resources.
  • Description of emerging methodologies for post-genomic research.

Main Results:

  • Identification of key resources for Aspergillus research.
  • Outline of methodologies to leverage genomic data.

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Conclusions:

  • The post-genomic era in Aspergillus promises significant advancements in understanding fungal biology.
  • Expected progress in biotechnological and medical applications of Aspergillus research.