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Immunotropic effects of active immunization with serotonin-protein conjugate in C57BL/6 mice exposed to
T V Davydova1, V G Fomina, L A Vetrile
1Institute of General Pathology and Pathophysiology, Russian Academy of Medical Sciences, Moscow.
Immobilization stress for 14 h induced lymphopenia, hypoplasia of the thymus and spleen, and decrease in functional activity of T lymphocytes and macrophages in C57Bl/6 mice. Active induction of antibodies against serotonin during stress decreased functional activity of T lymphocytes and partially recovered phagocytic activity of peritoneal macrophages.
Immobilization stress for 14 h induced lymphopenia, hypoplasia of the thymus and spleen, and decrease in functional activity of T lymphocytes and macrophages in C57Bl/6 mice. Active induction of antibodies against serotonin during stress decreased functional activity of T lymphocytes and partially recovered phagocytic activity of peritoneal macrophages.
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