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Updated: Aug 21, 2026

Novel and Innovative Hybrid Technique for Type A Aortic Dissection
Published on: March 28, 2025
Stent graft treatment of thoracic aortic disease
Alessandro S Bortone1, Emanuela De Cillis, Donato D'Agostino
1Interventional Cardiology, Institute of Cardiac Surgery, Department of Emergency and Organ Transplantation, University of Bari School of Medicine, Bari, Italy.
Insights
Endovascular repair of thoracic aortic disease shows promising long-term outcomes and efficacy. This minimally invasive approach offers a valid alternative to medical management, particularly for complex aortic conditions.
Area of Science:
- Cardiovascular Surgery
- Vascular Surgery
- Interventional Radiology
Background:
- Thoracic aortic diseases encompass aneurysms, dissections, and traumatic injuries, posing significant clinical challenges.
- Traditional open surgical repair carries substantial risks, driving the need for less invasive alternatives.
- Endovascular management has emerged as a promising therapeutic strategy for these complex conditions.
Purpose of the Study:
- To evaluate the efficacy and long-term outcomes of endovascular management for various thoracic aortic diseases.
- To compare the outcomes of endovascular treatment with medical management for chronic type B dissections.
- To assess the safety and complication rates associated with endovascular stent-graft repair.
Main Methods:
- Retrospective analysis of 129 patients treated between March 1999 and August 2003.
- Patients were categorized into groups based on diagnosis: aneurysms, post-traumatic lesions, and type B dissections.
- Preoperative assessment included computed tomography (CT) scans and angiography; stent-graft deployment was guided by transesophageal echocardiography (TEE).
Main Results:
- Optimal stent-graft deployment was achieved in 95.3% of treated patients.
- The overall operative mortality rate was 3.7% (4 hospital deaths).
- During a mean follow-up of 20.8 months, the mortality rate in the endovascular group was 6.5%, significantly lower than the 31.8% in the medically managed group (p<0.001).
Conclusions:
- Endovascular management is an effective and safe treatment option for thoracic aortic diseases, including acute presentations.
- The procedure demonstrates favorable long-term outcomes and a reduced mortality rate compared to medical therapy.
- No spinal cord injuries or stent-graft-related complications were observed in this cohort.
Abstract:
This study was a retrospective analysis of both the efficacy and long-term outcome of endovascular management of thoracic aortic disease. From March 1999 to August 2003, 129 patients (110 males; 19 females) were enrolled. They were divided into four groups: aneurysms (41, 5 of which acutely ruptured, Group A), post-traumatic lesions (24, 14 acute and 10 chronic, Group B) and complicated type B dissections (42, 23 acute and 19 chronic, Group C). Twenty-two of the 129 patients with chronic type B dissection, not suitable for endovascular treatment, received medical management only (Group D). All patients underwent computed tomography (CT) scan and angiography as preoperative assessment. Stent-graft systems were Talent -Medtronic, Excluder-Gore, Zenith-Cook and Endofit-Endomed, deployed by transesophageal echocardiography (TEE) monitoring. An optimal deployment with sealing of the graft was achieved in 95.3% (102/107) of the treated patients discharged in good condition within 6 days. Five patients (3 in Group A and 2 in Group C) underwent endovascular completion of the elephant trunk technique successfully. In 5 patients affected by atherosclerotic aneurysm, in a single-time procedure, we have also treated the abdominal aortic aneurysm by endovascular. No spinal cord injuries were observed. The follow up (average: 20.82+/-10.01 months), performed with serial chest CT scans, was 100% complete. No stent-graft related complications were detected. In 2 patients with chronic dissection, an asymptomatic type II endoleak was detected. A total of 4 hospital deaths resulted in an overall operative mortality rate of 3.7%. Seven patients (6.5%) died during the follow-up period, whereas a 31.8% (7/22) mortality rate (p<0.001) was observed within the medical treatment group. Endovascular treatment of thoracic aortic diseases, even in the acute phase, may represent a valid option, especially when compared to medical therapy.
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