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The use of corticosteroids in dermatological practice
1Department of Dermatology, Royal Prince Alfred Hospital, Camperdown, NSW.
The Medical Journal of Australia
|March 16, 1992
Summary
Corticosteroids are widely used for skin diseases. Oral steroids treat severe systemic conditions, while topical steroids manage dermatitis and psoriasis, but overuse can cause side effects.
Area of Science:
- Dermatology
- Pharmacology
Background:
- Corticosteroids are frequently prescribed for various dermatological conditions.
- Understanding their efficacy and risks is crucial for patient management.
Purpose of the Study:
- To review the diverse applications of corticosteroids in treating skin diseases.
- To highlight the benefits and potential adverse effects of systemic and topical corticosteroid use.
Main Methods:
- A comprehensive literature search was conducted.
- 33 relevant studies published from 1950 onwards were selected for analysis.
Main Results:
- Systemic corticosteroids are effective for severe hypersensitivity, connective tissue, and blistering diseases.
- Topical corticosteroids are primary treatments for dermatitis and beneficial for psoriasis.
- Potential side effects include skin atrophy, hypothalamic-pituitary-adrenal suppression, and Cushing's syndrome with prolonged or excessive use.
Conclusions:
- Corticosteroids, both systemic and topical, are essential in managing numerous skin conditions.
- Appropriate use is key to maximizing benefits and minimizing adverse effects.
- Physicians must carefully weigh the risks and benefits for each patient.
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