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A peculiar acantholytic dermatosis
1Department of Dermatology, Kitazato University Medical School, Sagamihara-city, Japan.
Abstract:
This paper reports a peculiar case seen in a 36-year-old woman who every summer since the age of 30 has developed numerous solitary vesicles or crusted papules with intense pruritus in the seborrheic zones. There are no general symptoms and no hereditary relations. The individual rash disappears completely in a week to a month and there is no eruption in winter. The clinical picture resembles that of Darier's disease, but histopathological tests reveal intraepidermal cleft or bulla formation due to acantholysis but no dyskeratosis. Clinicopathological consideration indicates a disease akin to familial benign chronic pemphigus, but as our case does not correspond to any known disease, it is therefore reported as a peculiar acantholytic dermatosis.
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