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Related Experiment Videos

Assessment of ventricular repolarization in a large group of children with early onset deafness.

Ercan Tutar1, Mustafa Tekin, Tayfun Uçar

  • 1Ankara University School of Medicine, Division of Pediatric Cardiology, Ankara, Turkey. tutor@dialup.ankara.edu.tr

Pacing and Clinical Electrophysiology : PACE
|October 6, 2004
PubMed
Summary

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This study found no significant repolarization abnormalities in deaf children compared to hearing children when heart rates are similar. Routine ECG screening for these parameters is likely unnecessary for deaf children without specific risk factors.

Area of Science:

  • Pediatric Cardiology
  • Otolaryngology
  • Clinical Electrophysiology

Background:

  • Congenital sensorineural deafness is a significant condition affecting many children.
  • Previous research has not conclusively determined if deafness is associated with cardiac repolarization abnormalities.
  • Jervell and Lange-Nielsen syndrome (JLNS), a cause of prolonged QT interval, was excluded from this study.

Purpose of the Study:

  • To investigate potential differences in cardiac repolarization parameters between deaf and hearing children.
  • To determine if congenital sensorineural deafness is independently associated with QT interval abnormalities.
  • To assess the need for routine electrocardiogram (ECG) screening in deaf children.

Main Methods:

  • Electrocardiograms (ECGs) were analyzed from 397 deaf children and 361 normal-hearing children.

Related Experiment Videos

  • QT and QTc intervals, along with their dispersions, were measured by an observer blinded to hearing status.
  • Data were compared between groups and re-analyzed after stratifying by heart rate.

    • Main Results:

    • Deaf children exhibited longer mean QT intervals but shorter mean QTc intervals compared to controls.
    • Deaf children had a significantly lower mean heart rate.
    • Differences in QT and QTc intervals became insignificant or disappeared when heart rate differences were accounted for.

    Conclusions:

    • Children with congenital sensorineural deafness do not show major cardiac repolarization abnormalities when compared to hearing children with similar heart rates.
    • Routine ECG screening for repolarization abnormalities in deaf children is not recommended unless specific risk factors like syncope are present.
    • Further research may focus on specific subgroups or risk stratification for cardiac events in deaf populations.