Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Tissue engineering through autologous mesenchymal stem cells.

Christian Jorgensen1, Jan Gordeladze, Danielle Noel

  • 1Service d'Immuno-Rhumatologie, Hôpital Lapeyronie, 34295 Montpellier, Cedex 5, France. jorgens@montp.inserm.fr

Current Opinion in Biotechnology
|October 7, 2004
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Phenotype-specific muscle proteomic profiling in titinopathies.

Acta neuropathologica communications·2026
Same author

Guidelines for Comparing Circular Dichroism Spectroscopy and Molecular Dynamics Simulations for Biomolecules.

Chemphyschem : a European journal of chemical physics and physical chemistry·2026
Same author

Non-destructive pipeline for analysis of crystalline solid dispersions.

International journal of pharmaceutics·2026
Same author

Intracranial and Peripheral Inflammatory Biomarkers Predict Futile Recanalization After Endovascular Treatment.

Stroke·2026
Same author

Generation of BBSOAS patient-specific induced pluripotent stem cell lines harboring six NR2F1 pathogenic variants.

Stem cell research·2026
Same author

Mammalian mesenchymal stromal cells enhance zebrafish fin regeneration.

Cell regeneration (London, England)·2026

Mesenchymal stem cells (MSCs) show promise for cartilage regeneration. Combining MSCs with biomaterials and differentiating factors may enhance tissue repair for joint diseases like osteoarthritis.

Area of Science:

  • Regenerative Medicine
  • Biomaterials Science
  • Stem Cell Biology

Background:

  • Cartilage regeneration is crucial for treating joint pathologies.
  • Mesenchymal stem cells (MSCs) are multipotent progenitors with potential for tissue repair.
  • Current limitations in complete healing necessitate advanced therapeutic strategies.

Purpose of the Study:

  • To explore the potential of Mesenchymal stem cells (MSCs) for cartilage regeneration.
  • To investigate the combined use of MSCs, scaffolds, and differentiating factors for enhanced tissue repair.
  • To highlight the need for further research on the long-term behavior of MSCs in pathological joints.

Main Methods:

  • Utilizing Mesenchymal stem cells (MSCs) as a cell-based therapy.
  • Employing biomaterial scaffolds to support tissue regeneration.

Related Experiment Videos

  • Investigating the role of selective differentiating factors in promoting cartilage formation.

    • Main Results:

    • Mesenchymal stem cells (MSCs) are readily available and expandable for therapeutic use.
    • Combined approaches involving MSCs, scaffolds, and differentiating factors show potential for achieving full tissue healing.
    • The integration and long-term behavior of MSCs with biomaterials in diseased joints require further study.

    Conclusions:

    • Mesenchymal stem cells (MSCs) represent a promising avenue for cartilage regeneration.
    • A combination therapy approach may be necessary to achieve complete and functional tissue repair.
    • Further investigation into the in vivo performance of MSC-biomaterial constructs is essential before clinical application in osteoarthritis and rheumatoid arthritis.