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Updated: Aug 21, 2026

Repetitive Transcranial Magnetic Stimulation to the Unilateral Hemisphere of Rat Brain
Published on: October 22, 2016
Intravenous anaesthesia and repetitive transcranial magnetic stimulation monitoring in spinal column surgery
1Spinal Injuries Unit, Southport and Ormskirk Hospital NHS Trust, Town Lane, Southport PR8 6PN, UK.
Background:
Transcranial magnetic stimulation with motor evoked potential monitoring is a non-invasive method for monitoring motor tracts during surgery. However, anaesthetic agents such as propofol and volatile agents reduce responses to single transcranial magnetic stimulation. We assessed an intravenous technique for anaesthesia to allow motor evoked potentials (MEPs) to be monitored using repetitive transcranial magnetic stimulation (rTMS).
Methods:
We applied three-pulse rTMS (TriStim) in 11 patients undergoing spinal column surgery after spinal column injury and recorded the latency and peak-to-peak amplitude of MEPs. Anaesthesia was maintained with propofol and remifentanil.
Results:
MEPs were monitored successfully intraoperatively in all patients.
Conclusions:
It is possible to monitor intraoperative MEP using rTMS during anaesthesia with propofol and remifentanil.

