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Updated: Aug 21, 2026

Microsurgical Clip Obliteration of Middle Cerebral Aneurysm Using Intraoperative Flow Assessment
Published on: September 25, 2009
Multiple cerebral aneurysms and subarachnoid hemorrhage in a patient with Alagille syndrome
Hans-Georg Schlosser1, Thoralf Kerner, Christian Woiciechowsky
1Department of Neurosurgery, Charité, Virchow-Clinic, Humboldt-University of Berlin, Berlin, Germany.
Abstract:
Although intracranial hemorrhage has frequently been found responsible for mortality in adult patients with Alagille syndrome (AGS), no specific underlying cause has been identified. We describe the case of severe subarachnoid hemorrhage in a 30-year-old woman harboring five intracranial aneurysms and multiple peripheral vascular anomalies. To evaluate a possible higher incidence of intracranial aneurysms, a study of the cerebral vasculature in all AGS patients by using noninvasive imaging techniques should be considered.
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