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Updated: Aug 21, 2026

In Vivo Monitoring of Transcriptional Activity During Metabolic Transition Using a Bioluminescent Reporter in Yeast
Published on: February 21, 2025
[Effect of glucose on luciferase expression in Photobacterium leiognathi]
Toshihiko Watanabe1, Takuya Suzuki, Naoki Yoshikawa
1Department of Microbiology, Tohoku Pharmaceutical University, Aoba-ku, Sendai 981-8558, Japan.
Abstract:
Photobacterium leiognathi cultured in marine broth emits a luminescence that is temporarily enhanced and then extinguished by glucose. Glucose reduces the luciferase level and the expression of lux ABG mRNA in P. leiognathi. The amount of ATP in P. leiognathi is temporarily increased and then declines to the normal level. These results indicate that the extinguishing by glucose in P. leiognathi is induced by the interruption of the translation of luciferase.

