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Vasculitis associated with the use of leflunomide
Jeannie Macdonald1, Toni Zhong, Adriana Lazarescu
1Department of Medicine, The University of Western Ontario, London, Ontario, Canada.
The Journal of Rheumatology
|October 7, 2004
Abstract:
Vasculitis as a complication of leflunomide therapy in the treatment of rheumatoid arthritis has been reported. We describe a case of acute necrotizing vasculitis following leflunomide therapy. Characteristics of this case and 4 cases in the literature suggest that vasculitis may be a rare but serious adverse effect of leflunomide therapy.