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Microscopy-based Assays for High-throughput Screening of Host Factors Involved in Brucella Infection of Hela Cells
Published on: August 5, 2016
[Bacteremia by Brucella canis. Isolation with the Bact-Alert system]
R Soloaga1, A Salinas, M Poterallo
1Pontificia Universidad Católica Argentina. rnsoloaga@yahoo.com
Revista Argentina De Microbiologia
|October 9, 2004
Summary
Brucella canis infrequently causes human disease, but this case highlights a successful treatment of a 15-year-old male. Prompt diagnosis and antibiotic therapy led to a full recovery, emphasizing the importance of considering this zoonotic infection.
Area of Science:
- Veterinary Medicine
- Infectious Diseases
- Zoonotic Infections
Background:
- Brucella canis, a species of Brucella, can cause disease in humans, although infrequently.
- Canine brucellosis is prevalent in many regions, posing a potential zoonotic risk.
Observation:
- A 15-year-old male presented with prolonged fever and generalized lymphadenopathy.
- Physical examination revealed hepatomegaly and lymphadenomegalies; ultrasonography showed splenomegaly.
- Blood cultures were positive for Brucella species.
Findings:
- The causative agent was identified as Brucella canis.
- The patient responded well to ceftriaxone, followed by doxycycline and rifampin.
- Complete resolution of symptoms was achieved without bone compromise.
Implications:
- This case underscores the importance of considering Brucella canis in the differential diagnosis of febrile illnesses, even when rare.
- Early diagnosis and appropriate antibiotic treatment are crucial for favorable outcomes in human brucellosis.
- Effective management strategies can lead to complete recovery, preventing long-term complications.
