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1Department of Pharmacology, School of Medicine, University of California, Davis, Davis, CA 95616, USA.
Neuron
|October 12, 2004
Abstract:
Recent studies have provided detailed structures of the N-terminal T1 domain of Kv channel alpha subunits that mediates contranslational subunit assembly. In this issue of Neuron, Kosolapov et al. probe T1 domain structure within the ribosomal tunnel. They find that the T1 domain forms secondary structure within the tunnel, in preparation for its immediate role in governing channel assembly upon exit.

