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Updated: Aug 21, 2026

Candidate Gene Testing in Clinical Cohort Studies with Multiplexed Genotyping and Mass Spectrometry
Published on: June 21, 2018
Effects of individual and family functioning on interest in genetic testing
Deborah J Bowen1, Emily Bourcier, Nancy Press
1Fred Hutchinson Cancer Research Center, Seattle, Wash. 98109, USA. dbowen@fhcrc.org
Objective:
The present study reports on the important issue of how family communication and support regarding breast cancer risk affects interest in genetic testing and mental health.
Methods:
Participants (n = 221) were women aged 18-74 who had at least one relative of Ashkenazi Jewish descent, no personal history of breast or ovarian cancer, and lived within 60 miles of Seattle, Wash.
Results:
Communication about breast cancer risk was reported with very low frequency across all types of relatives. Women talked with their mothers and sisters more often than their fathers, brothers, or children. The only significant predictor of interest in genetic testing was the individual level variable of seeking social support.
Conclusion:
Social support needs might be a part of the genetic testing process.
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