Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Research applications of the Cambridge Structural Database (CSD).

Frank H Allen1, Robin Taylor

  • 1Cambridge Crystallographic Data Centre (CCDC), 12 Union Road, Cambridge, UK. allen@ccdc.cam.ac.uk

Chemical Society Reviews
|October 14, 2004
PubMed
Summary

The Cambridge Structural Database (CSD) offers valuable crystal structure data for small molecules. This data aids in understanding molecular dimensions, conformations, and interactions, supporting drug design and chemical research.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Creative Futures in Education: Building 'Imagination Infrastructures' for Microbiology and Beyond.

Microbial biotechnology·2025
Same author

Correspondence on "Taxonomy of Chemical Bondings: Opportunities and Challenges".

Angewandte Chemie (International ed. in English)·2025
Same author

Strengthening the Capacity of Service Providers to Reduce the Impact of the COVID-19 Pandemic on African, Caribbean, and Black Communities: Protocol for the COVID-19 African, Caribbean, and Black Providers Project 2.0 Implementation and Evaluation.

JMIR research protocols·2025
Same author

Oculomics: A Crusade Against the Four Horsemen of Chronic Disease.

Ophthalmology and therapy·2024
Same author

Molecular Dynamics Study of the Aggregation Behavior of <i>N</i>,<i>N</i>,<i>N</i>',<i>N</i>'-Tetraoctyl Diglycolamide.

The journal of physical chemistry. B·2022
Same author

Sustainability and Justice: Challenges and Opportunities for an Open STEM Education.

CBE life sciences education·2022

Area of Science:

  • Chemistry
  • Structural Chemistry
  • Drug Design

Background:

  • Crystal structure data are vital across scientific disciplines.
  • The Cambridge Structural Database (CSD) houses over 300,000 small organic and metal-organic compound structures.

Purpose of the Study:

  • To review the applications of CSD data.
  • To highlight the utility of derived structural knowledge libraries.

Main Methods:

  • Summarizing applications of CSD data.
  • Utilizing data to create Mogul (intramolecular) and IsoStar (intermolecular) libraries.

Main Results:

  • CSD data directly informs molecular dimensions, conformational preferences, and intermolecular interactions.

Related Experiment Videos

  • Mogul and IsoStar provide readily accessible structural knowledge.
  • These libraries support various software applications in chemistry.

    • Conclusions:

    • The CSD is a crucial resource for structural chemistry and rational drug design.
    • Derived electronic libraries enhance the accessibility and application of structural data.
    • This facilitates advancements in small-molecule and biological chemistry research.