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Intravitreal Injection and Quantitation of Infection Parameters in a Mouse Model of Bacterial Endophthalmitis
Published on: February 6, 2021
[Listeria endophthalmitis]
E Berger1, M Donat, R F Guthoff
1Augenklinik und Poliklinik, Universität, Rostock. eike.berger@med.uni-rostock.de
Abstract:
Listeria monocytogenes is a rare cause of endogenous endophthalmitis. During the last 20 years about 30 cases have been published, all of which showed similar clinical features and a profound visual loss mainly owing to delayed diagnosis. This case report is about an otherwise healthy 41-year-old woman whose diagnosis was established 17 days after the onset of symptoms by microbiological cultures. Under sufficient therapy signs of local inflammation disappeared and intraocular pressure decreased. Pars plana vitrectomy was necessary; although post-surgery complications developed, the result was complete recovery of visual acuity.
Insights
Listeria monocytogenes can cause endogenous endophthalmitis, leading to severe vision loss. Early diagnosis and treatment are crucial for recovery, as demonstrated in this case report.
Area of Science:
- Ophthalmology
- Infectious Diseases
Background:
- Endogenous endophthalmitis is a severe intraocular infection.
- Listeria monocytogenes is an uncommon but significant pathogen in endophthalmitis.
Observation:
- A 41-year-old woman presented with symptoms of endophthalmitis.
- Diagnosis was delayed by 17 days, confirmed by microbiological cultures.
- The patient experienced profound visual loss.
Findings:
- Prompt therapy led to decreased inflammation and intraocular pressure.
- Pars plana vitrectomy was required for treatment.
- Despite post-surgery complications, complete visual recovery was achieved.
Implications:
- This case highlights the importance of timely diagnosis and intervention for Listeria monocytogenes endophthalmitis.
- Aggressive management, including vitrectomy, can lead to favorable visual outcomes.
- Increased awareness of this rare condition is necessary for ophthalmologists.
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