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Circadian changes in heart rate turbulence parameters

Iwona Cygankiewicz1, Jerzy Krzysztof Wranicz, Halina Bolinska

  • 1Institute of Cardiology, Medical University of Lodz, Poland.

Journal of Electrocardiology
|October 16, 2004
PubMed

Insights

Heart rate turbulence (HRT) shows circadian patterns, with turbulence slope (TS) values being lowest in the afternoon. This finding is crucial for identifying cardiac death risk in coronary patients.

Area of Science:

  • Cardiology
  • Chronobiology
  • Medical Monitoring

Background:

  • Heart rate turbulence (HRT) is an emerging method for assessing cardiac death risk.
  • Previous research has not investigated the circadian variations of HRT parameters.

Purpose of the Study:

  • To investigate the circadian changes in heart rate turbulence (HRT) and heart rate variability (HRV) in patients with coronary artery disease.
  • To determine if specific times of day are associated with altered HRT or HRV values.

Main Methods:

  • Forty-six coronary patients with frequent ventricular premature beats underwent 24-hour Holter monitoring.
  • Turbulence onset (TO), turbulence slope (TS), and HRV parameters were analyzed across three 4-hour periods: morning, afternoon, and night.

Main Results:

  • No significant circadian changes were observed for turbulence onset (TO).
  • Turbulence slope (TS) values were significantly lower in the afternoon (5.08 ms/RR) compared to morning (7.08 ms/RR) and night (7.99 ms/RR) hours.
  • Certain heart rate variability parameters also exhibited reduced values during the afternoon.

Conclusions:

  • Turbulence slope (TS) demonstrates a circadian pattern in hospitalized patients with stable coronary artery disease.
  • The lowest TS values occur in the afternoon, suggesting potential diurnal variations in cardiovascular risk assessment.

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