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Peptide:MHC Tetramer-based Enrichment of Epitope-specific T cells
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Published on: October 22, 2012

T-cell epitope peptide vaccines

Sherine F Elsawa1, David A Rodeberg, Esteban Celis

  • 1Department of Immunology, Mayo Clinic, Rochester, MN, USA. elsawa.sherine@mayo.edu

Expert Review of Vaccines
|October 16, 2004
PubMed

T-cell immunotherapy is a promising treatment option for cancer. The identification of tumor antigens that are recognized by the immune system has allowed for the generation of vaccines for various malignancies. Due to the ease of manufacturing and characterizating peptide-based vaccines they have been used to stimulate antitumor T-cells. This article will review the use of peptide-based vaccines for the treatment of cancer by inducing antitumor T-lymphocyte responses.

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