Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Stress responsivity in children with externalizing behavior disorders.

Heddeke Snoek1, Stephanie H M Van Goozen, Walter Matthys

  • 1University Medical Center Utrecht, Rudolf Magnus Institute for Neurosciences, The Netherlands. h.snoek@psych.azu.nl

Development and Psychopathology
|October 19, 2004
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

The effect of patients' feedback on treatment outcome in a child and adolescent psychiatric sample: a randomized controlled trial.

European child & adolescent psychiatry·2018
Same author

Social-cognitive research in children with aggressive behaviour: New perspectives.

European child & adolescent psychiatry·2018
Same author

Individual prediction of long-term outcome in adolescents at ultra-high risk for psychosis: Applying machine learning techniques to brain imaging data.

Human brain mapping·2016
Same author

Brain development in adolescents at ultra-high risk for psychosis: Longitudinal changes related to resilience.

NeuroImage. Clinical·2016
Same author

[Formula: see text]Executive functioning and its relation to ASD and ADHD symptomatology in 22q11.2 deletion syndrome.

Child neuropsychology : a journal on normal and abnormal development in childhood and adolescence·2016
Same author

Magnetic resonance imaging studies on autism and childhood-onset schizophrenia in children and adolescents - a review.

Acta neuropsychiatrica·2016

Children with oppositional defiant disorder (ODD) and ODD with comorbid ADHD show weaker cortisol responses to stress. These autonomic nervous system (ANS) and hypothalamic-pituitary-adrenal (HPA) axis differences help distinguish ODD from attention-deficit/hyperactivity disorder (ADHD).

Area of Science:

  • Child psychiatry
  • Neuroscience
  • Psychophysiology

Background:

  • Children with oppositional defiant disorder (ODD) exhibit altered autonomic nervous system (ANS) and hypothalamic-pituitary-adrenal (HPA) axis activity.
  • Understanding these physiological patterns is crucial for differentiating ODD from attention-deficit/hyperactivity disorder (ADHD).

Purpose of the Study:

  • To investigate differences in ANS and HPA axis activity between children with ADHD, ODD, and comorbid ODD/ADHD under baseline and stress conditions.
  • To determine if physiological responses can differentiate between these externalizing behavior disorders.

Main Methods:

  • Studied cortisol, heart rate (HR), and skin conductance level (SCL) in 95 children (26 normal controls, 15 ODD, 31 ODD/ADHD, 23 ADHD) during stress.
  • Compared physiological responses across groups, including the effects of methylphenidate medication.

Related Experiment Videos

Main Results:

  • No baseline cortisol differences were observed between the four groups.
  • ODD and ODD/ADHD groups exhibited a significantly weaker cortisol stress response compared to ADHD and normal control groups.
  • ODD group showed significantly lower HR; externalizing groups had lower SCL, with no differences among them.

Conclusions:

  • Cortisol responsivity during stress is a key differentiator between ODD and ADHD in children with externalizing behaviors.
  • Physiological patterns, particularly HPA axis response, offer insights into the distinct neurobiology of ODD and ADHD.